11, August 2025

Curcuma longa and zinc oxide nanocomposite diet: A protective strategy against microplastic stress in Zebrafish (Danio rerio)

Author(s): 1.M. Swarnalatha, 2. M. Ramaswamy

Authors Affiliations:

1Associate Professor, Department of Zoology, Emerald Heights College for Women Ooty, The Nilgiris, TamilNadu. India.

2 (Retired), PG &Research Department of Zoology, Govt Arts College (Autonomous), Coimbatore, TamilNadu. India

DOIs:10.2017/IJRCS/202508005     |     Paper ID: IJRCS202508005


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Abstract:  The increasing prevalence of microplastics in aquatic ecosystems poses a significant threat to fish health and aquatic biodiversity. This study investigates the protective effects of zebrafish (Danio rerio) feed enriched with Curcuma longa (turmeric) and zinc oxide (ZnO) nanoparticles against microplastic-induced toxicity. Curcuma longa is known for its antioxidant and anti-inflammatory properties, while ZnO nanoparticles have demonstrated antimicrobial and protective cellular effects. Zebrafish were exposed to microplastics and simultaneously administered the enriched diet to evaluate physiological, histological, and behavioral responses. The results indicated that the supplemented feed mitigated oxidative stress, improved immune response, and reduced tissue damage caused by microplastics. This suggests a synergistic protective role of Curcuma longa and ZnO nanoparticles in enhancing fish resilience against environmental pollutants. The study highlights a promising, eco-friendly dietary intervention to reduce the impact of microplastic contamination in aquaculture and natural aquatic systems.    
Key Words:  Curcuma longa, Zinc oxide nanoparticles (ZnO NPs), Zebrafish (Danio rerio), Microplastics and Antioxidant activity

M. Swarnalatha, M. Ramaswamy(2025); Curcuma longa and zinc oxide nanocomposite diet: A protective strategy against microplastic stress in Zebrafish (Danio rerio), International Journal of Research Culture Society,    ISSN(O): 2456-6683,  Volume – 9,   Issue –  7,  Pp.30-35       Available on – https://ijrcs.org/


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