Nurses’ practice related to administration of intravenous albumin therapy among patients with chronic liver disease, with a view to develop a standard operating procedure based on the deficiencies in the nurses’ practice
Author(s): 1. Priyanka Rana 2. Madhavi Verma 3. Ankur Jindal
Authors Affiliations:
- M.Sc. Nursing Student, College of Nursing, Institute of liver and biliary sciences, India
2. Reader, Faculty, College of Nursing, Institute of liver and biliary sciences, New Delhi, India
3. Department of Hepatology, Associate professor, Institute of liver and biliary sciences, New Delhi, India
DOIs:10.2017/IJRCS/202603011     |     Paper ID: IJRCS202603011Abstract: Background : Human serum albumin is a common colloid used for volume expansion, albumin replacement and plasmapheresis. anaphylactic reaction to colloids are uncommon, and hypersenstivity reaction to HSA are even rarer. The application of a nursing care protocol in case of an adverse reaction to albumin can help in early management of the reaction and can improve practice linked to albumin therapy and raising nursing standards. Objective-To assess the Nurses’ Practice related to administration of IV albumin therapy among patients with Chronic Liver Disease, with a view to develop a Standard Operating procedure based on the defieciences in the Nurses’ Practice. Methods : Using a quantitative approach, an observational study was conducted. The total enumeration sampling technique was used to enrol 336 patients and 91 nurses who were directly involved in the patient care and administering IV albumin therapy An observation checlist was prepared for nursing practice also for patients to assess the frequency of adverse reaction. Result : Nurse’ mean practice score is 75.00. The highest possible score was 100, with the lowest score was 0, in terms of administration of albumin therapy, 28.57% nurses had poor practice, whereas 40.65% had average practice, only 6.59% of nurses had very good practice and 24.17% had a good practice. Conclusion : The standard operating procedure was developed that will enhance the nurses’ practice and lead to early identification of adverse reaction.
Priyanka Rana, Madhavi Verma, Ankur Jindal (2026); Nurses’ practice related to administration of intravenous albumin therapy among patients with chronic liver disease, with a view to develop a standard operating procedure based on the deficiencies in the nurses’ practice, International Journal of Research Culture Society, ISSN(O): 2456-6683, Volume – 10, Issue – 3, Available on – https://ijrcs.org/
- Bernardi, M., Angeli, P., Claria, J., Moreau, R., Gines, P., Jalan, R., Caraceni, P., Fernandez, J., Gerbes, A. L., O’Brien, A. J., Trebicka, J., Thevenot, T., & Arroyo, V. (2020). Albumin in decompensated cirrhosis: New concepts and perspectives. Gut, 69(6), 1127–1138
- Fasano, M., Curry, S., Terreno, E., Galliano, M., Fanali, G., Narciso, P., Notari, S. and Ascenzi, P., 2005. The extraordinary ligand binding properties of human serum albumin. IUBMB Life (International Union of Biochemistry and Molecular Biology: Life), 57(12), pp.787-796.
- D’Amico, G., Morabito, A., D’Amico, M., Pasta, L., Malizia, G., Rebora, P. and Valsecchi, M., 2017. New concepts on the clinical course and stratification of compensated and decompensated cirrhosis. Hepatology International, 12(S1), pp.34-43.
- Nafisi, S., Akhavan, S., Shiva, A., Ghasempour, M., Dariush, P., Makhdoomi, K., & Hatamkhani, S. (2020). Evaluation of human albumin use pattern in a referral teaching hospital. Journal of Pharmaceutical Care. https://doi.org/10.18502/jpc.v7i3.2350
- Wang, K. Y., Friedman, D. F., & DaVeiga, S. P. (2019). Immediate hypersensitivity reaction to human serum albumin in a child undergoing plasmapheresis. Transfusion, 59(6), 1921-1923.
- Eljaiek, R., Heylbroeck, C. Dubois, M.-J. (2017). Albumin administration for fluid resuscitation in burn patients: A systematic review and meta-analysis. Burns, 43(1), 17–24.
- Eastwood, G. M., Peck, L., Young, H., Paton, E., Glassford, N. J., Zhang, L., Zhu, G., Tanaka, A., & Bellomo, R. (2015). Intensive Care Nurses’ self-reported practice of intravenous fluid bolus therapy. Intensive and Critical Care Nursing, 31(6), 352–358. https://doi.org/10.1016/j.iccn.2015.06.001
- Lamsal, S., & Shrestha, R. (2021). Nurses’ knowledge and practice regarding intravenous therapy in a teaching hospital, Bharatpur. Journal of Chitwan Medical College, 9(1), 13–19. https://doi.org/10.54530/jcmc.385

