INTERNATIONAL JOURNAL OF RESEARCH CULTURE SOCIETY

: Guillain–Barré syndrome (GBS) is an acute immune-mediated peripheral neuropathy that can progress rapidly to severe weakness and respiratory and autonomic complications. This case report describes a 42-year-old woman who presented with generalized body swelling for 15 days, loose stools for 2 days, and progressive weakness of all four limbs for 5 days. Initial investigations revealed hypokalaemia, elevated creatine phosphokinase, transaminitis, hypothyroidism with elevated thyroid-stimulating hormone, hypoalbuminemia, and pyuria. In view of progressive areflexic quadriparesis following an antecedent diarrheal illness, GBS was suspected. Urine culture grew Escherichia coli and Candida albicans. Nerve conduction studies demonstrated motor-predominant sensorimotor axonal polyneuropathy, predominantly involving the upper limbs, consistent with the acute motor axonal neuropathy variant of GBS. The patient received intravenous immunoglobulin, correction of electrolyte abnormalities, physiotherapy, and rehabilitation. Nursing care focused on respiratory monitoring, fall prevention, promotion of physical mobility, monitoring of fluid and electrolyte balance, maintenance of skin integrity, and patient and caregiver education. The patient showed gradual improvement in muscle strength, particularly in the upper limbs, and reduction in generalized edema. This case highlights the importance of early recognition, timely treatment, vigilant nursing assessment, prevention of complications, rehabilitation, and multidisciplinary care in patients with GBS.

KEY WORDS - Guillain–Barré syndrome, Health Education, comprehensive nursing care, Variants, Rehabilitation.