15, May 2026

Prader-Willi Syndrome: A Comprehensive Review

VOLUME-10; ISSUE-5; MAY-2026

Author(s): Ms. Chetna Kumari, Ms. Santosh Kumari, Ms. Shaweta Sharma, Ms. Kavita Verma, Ms. Dimple Chauhan

Authors Affiliations:

*1Associate Professor, Department of Child Health Nursing, M.M. College of Nursing, Maharishi Markandeshwar University, Kumarhatti, Solan, Himachal Pradesh, India.

1Associate Professor, Department of Obstetrics and Gynaecological Nursing, M.M. College of Nursing, Maharishi Markandeshwar University, Kumarhatti, Solan, Himachal Pradesh, India.

2Clinical Instructor, Army College of Nursing, Jalandhar Cantt, Punjab, India

3Assistant Professor, Department of Child Health Nursing, M.M. College of Nursing, Maharishi Markandeshwar University, Kumarhatti, Solan, Himachal Pradesh, India.

4 Nursing Tutor, Department of Child Health Nursing, M.M. College of Nursing, Maharishi Markandeshwar University, Kumarhatti, Solan, Himachal Pradesh, India.

DOIs:10.2017/IJRCS/202605008     |     Paper ID: IJRCS202605008


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Prader-Willi syndrome (PWS) is a multisystem genetic disorder caused by the loss of paternally expressed genes on chromosome, that can lead to a wide array of symptoms, including obesity and developmental delays. It is caused by genetic changes on an "unstable" region of chromosome 15 that affects the regulation of gene expression. It has mostly occurred in babies whose mothers age is over 35 years of age. It mostly causes developmental delay and intellectual disability, behavioural  difficulties, hyperphagia and obesity with food behavioural anomalies. It only diagnosed with genetic counselling. There is currently no treatment for this syndrome, treatment focused on managing symptoms and improving quality of life through early intervention and with behavioural therapies.

Prader-Willi syndrome (PWS), Genetic Disorder, Children

Ms. Chetna Kumari, Ms. Santosh Kumari, Ms. Shaweta Sharma, Ms. Kavita Verma, Ms. Dimple Chauhan, Prader-Willi Syndrome: A Comprehensive Review, International Journal of Research Culture Society,    ISSN(O): 2456-6683,  Volume – 10,   Issue –  5,  Available on – https://ijrcs.org/

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